Analytical InstrumentsNarrow moat

Thermo Fisher Scientific (TMO) — moat facet

Analytical Instruments sells the machines, which makes it Thermo Fisher's most cyclical segment and the one most exposed to tariffs and specialist rivals.

Analytical Instruments is the segment that sells machines, and it carries most of Thermo Fisher's instrument risk. Revenue was $7,554 million in 20251, and segment income $1,736 million, a 23.0% margin, down from 26.2% in 20242.

Analytical Instruments segment margin (%)19.1%201521.3%201723.1%201915.8%202026.3%202326.2%202423.0%2025Thermo Fisher Forms 10-K FY2017-FY2025; calculated
A peak in 2023, then tariffs.

It has three businesses. Chromatography and mass spectrometry had revenue of $3,360 million in 2025, chemical analysis $1,237 million and electron microscopy $2,957 million3. The last came largely from FEI, bought in 2016 for $4,082 million4.

The history is steady growth with one interruption. Revenue was $3,208 million in 20155, $4,821 million in 2017 with FEI6, and $5,522 million in 20197. In 2020 it fell to $5,124 million8 as laboratories closed, and the margin fell to 15.8%9. It then recovered to $7,463 million in 202410.

It is paid mostly per instrument, with service contracts and some consumables attached. That makes it the most cyclical segment: customers delay capital purchases when budgets are uncertain.

Profitability peaked in 2023 at 26.3%11. In 2025 the 10-K attributed the fall to "the impacts of tariffs and related foreign exchange, strategic investments, and unfavorable business mix"12. In the second quarter of 2026 the margin was 23.0% against 18.8% a year earlier13.

Growth has slowed. Revenue rose 2.8% in 2024 and 1.2% in 202514, with chemical analysis down $78 million15 and electron microscopy up from $2,870 million to $2,957 million16. The second quarter of 2026 was better: revenue of $1,847 million against $1,728 million17, and 7% organic growth18.

The outlook depends on capital budgets and on the proteomics software the company bought in 2026, which reports here. Rivals are the instrument specialists described on the competitors page.

The quarter's detail shows where growth came from. In the second quarter of 2026 chromatography and mass spectrometry revenue was $821 million against $784 million, chemical analysis $318 million against $292 million and electron microscopy $707 million against $652 million19. Segment income was $424 million against $325 million20. The segment spent $124 million on capital equipment in 202521, a small figure for a company that makes the machines others buy.

FEI was paid for in cash, $4,440 million22, and electron microscopy has been the segment's fastest-growing business over the past two years. MarketsandMarkets expects the instrumentation market to grow from USD 63.4 billion in 2025 to USD 92.53 billion by 203123, about 6.5% a year24; a third-party estimate, but faster than the segment's recent growth.

Pricing power is the question. A margin back below 20% in a year without a tariff shock would say the segment had lost pricing power to the specialists.

Moat trajectory: Holding steady

Margin 26.2% (2024) to 23.0% (2025); 23.0% in Q2 2026 from 18.8%.

The number that tests this moat
Reported
Analytical Instruments revenue, latest quarter
$1,847M, against $1,728M (Q2 2026)

Instrument demand; growth falling back toward 1% would mean capital budgets have tightened again.

Source: Thermo Fisher Q2 2026 results release ↗
References
  1. ReportedRevenue was $7,554 million in 2025, and segment income $1,736 million, a 23.0% margin, down from 26.2% in 2024.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - segment information: revenue, income, margins, assets and capital spending. — FY2025 · publ. 26 February 2026 · source ↗
  2. ReportedRevenue was $7,554 million in 2025, and segment income $1,736 million, a 23.0% margin, down from 26.2% in 2024.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - segment information: revenue, income, margins, assets and capital spending. — FY2025 · publ. 26 February 2026 · source ↗
  3. ReportedChromatography and mass spectrometry had revenue of $3,360 million in 2025, chemical analysis $1,237 million and electron microscopy $2,957 million.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - revenue by business. — FY2025 · publ. 26 February 2026 · source ↗
  4. ReportedThe last came largely from FEI, bought in 2016 for $4,082 million.
    Thermo Fisher Scientific Form 10-K for fiscal 2017 - segment revenue and income for 2015-2017, net income and EPS, service revenue, headcount and the FEI, Affymetrix and Patheon acquisitions. — FY2017 · publ. February 2018 · source ↗
  5. ReportedRevenue was $3,208 million in 2015, $4,821 million in 2017 with FEI, and $5,522 million in 2019.
    Thermo Fisher Scientific Form 10-K for fiscal 2017 - segment revenue and income for 2015-2017, net income and EPS, service revenue, headcount and the FEI, Affymetrix and Patheon acquisitions. — FY2017 · publ. February 2018 · source ↗
  6. ReportedRevenue was $3,208 million in 2015, $4,821 million in 2017 with FEI, and $5,522 million in 2019.
    Thermo Fisher Scientific Form 10-K for fiscal 2019 - segment income for 2017-2019, geography including China, backlog by segment and the statement that no customer accounted for more than 5% of revenue. — FY2019 · publ. February 2020 · source ↗
  7. ReportedRevenue was $3,208 million in 2015, $4,821 million in 2017 with FEI, and $5,522 million in 2019.
    Thermo Fisher Scientific Form 10-K for fiscal 2020 - segment revenue for 2018-2020, revenue by type and geography, COVID-19 revenue, headcount and remaining performance obligations. — FY2020 · publ. February 2021 · source ↗
  8. ReportedIn 2020 it fell to $5,124 million as laboratories closed, and the margin fell to 15.8%.
    Thermo Fisher Scientific Form 10-K for fiscal 2022 - segment revenue and income for 2020-2022, revenue by type and by geography including China, and COVID-19 testing revenue. — FY2022 · publ. February 2023 · source ↗
  9. Moat Explorer calcIn 2020 it fell to $5,124 million as laboratories closed, and the margin fell to 15.8%.
    Moat Explorer calculation from Thermo Fisher's reported financial statements, results releases, earnings calls and market data ($ millions unless stated). Revenue by type: consumables + services share (18,664 + 18,592) / 44,556 = 83.6% (2025); (12,576 + 5,490) / 24,358 = 74.2% (2018); (13,109 + 6,046) / 25,542 = 75.0% (2019); (18,527 + 6,912) / 32,218 = 79.0% (2020); (22,608 + 8,850) / 39,211 = 80.2% (2021); (20,624 + 16,367) / 44,915 = 82.4% (2022); (17,597 + 17,614) / 42,857 = 82.2% (2023); (17,587 + 17,845) / 42,879 = 82.6% (2024); H1 2026 (9,794 + 9,899) / 22,999 = 85.6%. Instruments 7,301 / 7,924 - 1 = -7.9% (2022-2025), a fall of 623. Consumables 18,664 / 17,587 - 1 = 6.1%. Services 18,592 / 17,845 - 1 = 4.2%. Gross margin by type 2025: products (25,965 - 13,405) / 25,965 = 48.4%; services (18,592 - 12,913) / 18,592 = 30.5%; total (44,556 - 13,405 - 12,913) / 44,556 = 40.9%. Businesses: BioProduction 2,652 / 2,923 - 1 = -9.3% (2024), 3,200 / 2,652 - 1 = 20.7% (2025), Q2 2026 941 / 745 - 1 = 26.3%. Biosciences 4,169 / 4,238 - 1 = -1.6%. Transplant 492 / 393 - 1 = 25.2%, Q2 134 / 124 - 1 = 8.1%. ImmunoDiagnostics 912 / 802 - 1 = 13.7%, Q2 248 / 234 - 1 = 6.0%. Clinical diagnostics 1,115 / 1,104 - 1 = 1.0%. Microbiology 645 / 618 - 1 = 4.4% (about 2.2% a year); sale price 1,075 / 645 = 1.7 times; microbiology / Specialty Diagnostics 645 / 4,676 = 13.8%. Research and safety channel 7,440 / 6,841 - 1 = 8.8%, Q2 2,036 / 1,883 - 1 = 8.1%, 7,440 - 6,841 = 599. Healthcare channel 1,788 / 1,712 - 1 = 4.4%, 1,788 / 1,764 - 1 = 1.4% (2025), Q2 442 / 407 - 1 = 8.6%. Laboratory products 2,407 / 2,613 - 1 = -7.9%. Channels (7,440 + 1,788) / 44,556 = 9,228 / 44,556 = 20.7%. Revenue growth: 44,556 / 42,879 - 1 = 3.9% (2025), increase 44,556 - 42,879 = 1,677; 44,556 / 42,857 - 1 = 4.0% (2023-2025); 44,556 / 16,965 = 2.6 times (2015-2025). Research channel share of the increase 422 / 1,677 = 25%. Eliminations / revenue 633 / 16,965 = 3.7% (2015), 2,033 / 44,556 = 4.6% (2025). Life Sciences Solutions sold to other segments 1,593 / 10,374 = 15.4%; external revenue 8,781 / 8,160 - 1 = 7.6%. Pharma services 7,142 / 6,685 - 1 = 6.8%; clinical research 7,915 / 7,836 - 1 = 1.0%; Q2 2026 clinical research 2,396 / 1,955 - 1 = 22.6%. Clinical research + pharma services 7,915 + 7,142 = 15,057, / 44,556 = 33.8% (2025); (7,836 + 6,685) / 42,879 = 33.9% (2024); (7,691 + 6,806) / 42,857 = 33.8% (2023); Q2 2026 2,396 + 1,893 = 4,289, / 11,994 = 35.8%; Q2 2025 1,955 + 1,794 = 3,749. Patheon + PPD + Clario 7,358 + 16,036 + 9,098 = 32,492. Clario price / 2025 revenue 9,098 / 1,500 = 6.1 times; 9,098 / 1,250 = 7.3 times; goodwill 5,934 / 9,098 = 65%. Filtration 3,870 / 750 = 5.2 times. LPBS capital expenditure 1,005 / 1,525 = 65.9%. Revenue per employee 32,218 / 80,000 = about $403,000 (2020); 44,556 / 125,000 = about $356,000 (2025); 356 / 403 - 1 = -12%. Remaining performance obligations 24.61 / 28.30 - 1 = -13.0% (2021-2024); 29.70 / 46.336 = 64% of trailing revenue. 2019 backlog 4,577 / 7,768 = 59%. Trailing twelve months to June 2026: revenue 44,556 - 21,219 + 22,999 = 46,336; net income 6,704 - 3,124 + 3,387 = 6,967. COVID: Life Sciences Solutions segment income 3,420 / 7,817 - 1 = -56%; testing 0.33 / 7.26 = 4.5% remaining. Tax rate 547 / 7,308 = 7.5% (2025); 657 / 7,037 = 9.3% (2024); 284 / 6,298 = 4.5% (2023). R&D 1,397 / 44,556 = 3.1%. Adjusted less GAAP EPS 22.87 - 17.74 = 5.13. Acquisitions booked since 2021: PPD 16,036 + PeproTech 1,864 + European viral vector 830 + Mesa Biotech 472 + The Binding Site 2,699 + CorEvitas 910 + Olink 3,146 + filtration and separation 3,870 + Clario 9,098 = 38,925. Goodwill and intangibles / total assets (54,832 + 18,606) / 113,174 = 73,438 / 113,174 = 65% (June 2026); (49,362 + 15,838) / 110,343 = 59% (end 2025). Genetic sciences 2,870 / 2,787 - 1 = 3.0%. Analytical Instruments 7,554 / 63,400 = 11.9% of the MarketsandMarkets estimate; revenue 7,463 / 7,263 - 1 = 2.8% (2024), 7,554 / 7,463 - 1 = 1.2% (2025), Q2 1,847 / 1,728 - 1 = 6.9%. Market value against Danaher 249.58 / 157.81 - 1 = 58%. China share of revenue 2,060 / 20,918 = 9.8% (2017), 2,752 / 25,542 = 10.8% (2019), 3,444 / 39,211 = 8.8% (2021), 3,793 / 44,915 = 8.4% (2022). Year-end P/E = market value / net income: 56.61 / 1.975 = 28.7 (2015), 55.74 / 2.022 = 27.6 (2016), 76.14 / 2.225 = 34.2 (2017), 90.09 / 2.938 = 30.7 (2018), 130.27 / 3.696 = 35.2 (2019), 184.61 / 6.375 = 29.0 (2020), 262.92 / 7.725 = 34.0 (2021), 215.98 / 6.950 = 31.1 (2022), 205.08 / 5.995 = 34.2 (2023), 198.99 / 6.335 = 31.4 (2024), 217.70 / 6.704 = 32.5 (2025), trailing 249.58 / 6.967 = 35.8. Segment margins = segment income / segment revenue: Life Sciences Solutions 1,414 / 4,774 = 29.6% (2015), 2,446 / 6,856 = 35.7% (2019), 7,817 / 15,631 = 50.0% (2021), 3,420 / 9,977 = 34.3% (2023), 3,503 / 9,631 = 36.4% (2024); Analytical Instruments 613 / 3,208 = 19.1% (2015), 1,027 / 4,821 = 21.3% (2017), 1,273 / 5,522 = 23.1% (2019), 808 / 5,124 = 15.8% (2020), 1,908 / 7,263 = 26.3% (2023); Specialty Diagnostics 873 / 3,244 = 26.9% (2015), 1,024 / 4,763 = 21.5% (2022); LPBS 922 / 6,372 = 14.5% (2015), 1,271 / 12,245 = 10.4% (2020), 1,844 / 14,862 = 12.4% (2021), 2,872 / 22,511 = 12.8% (2022), 3,358 / 23,041 = 14.6% (2023), 3,090 / 23,157 = 13.3% (2024). Segment shares 2025: Life Sciences Solutions income 3,768 / 10,109 = 37.3%, revenue 10,374 / 46,589 = 22.3%; LPBS external revenue 23,818 / 44,556 = 53.5%. Combined segment margin 10,109 / (44,556 + 2,033) = 10,109 / 46,589 = 21.7%. Segment growth: Life Sciences Solutions 10,374 / 9,631 - 1 = 7.7% (2025), Q2 2026 2,815 / 2,499 - 1 = 12.6%; Specialty Diagnostics 4,676 / 4,512 - 1 = 3.6% (2025), Q2 1,205 / 1,134 - 1 = 6.3%; LPBS 23,984 / 23,157 - 1 = 3.6% (2025), Q2 6,693 / 5,995 - 1 = 11.6%. Ten-year compound growth 2015-2025: Life Sciences Solutions (10,374 / 4,774)^(1/10) - 1 = 8.1%; Specialty Diagnostics (4,676 / 3,244)^(1/10) - 1 = 3.7%; LPBS (23,984 / 6,372)^(1/10) - 1 = 14.2%. Additional: return on equity 6,704 / ((53,407 + 49,584) / 2) = 13.0% (2025). Instruments share 6,292 / 24,358 = 25.8% (2018), 3,305 / 22,999 = 14.4% (H1 2026). Life Sciences Solutions segment income Q2 1,041 / 919 - 1 = 13.3%. Services share 2,297 / 16,965 = 13.5% (2015), 18,592 / 44,556 = 41.7% (2025). Service gross margin (17,614 - 12,589) / 17,614 = 28.5% (2023), (17,845 - 12,654) / 17,845 = 29.1% (2024); product (25,034 - 12,523) / 25,034 = 50.0% (2024). LPBS growth 23,984 - 23,157 = 827 = 457 + 422 - 118 (laboratory products) + 79 (clinical research) - 13 (eliminations). Eliminations 3,010 / 39,211 = 7.7% (2021). Europe 11,826 / 10,741 - 1 = 10.1%; North America 23,033 / 22,764 - 1 = 1.2% (2023-2025). Headcount 125,000 / 122,000 - 1 = 2.5%. Electron microscopy 2,957 / 2,564 - 1 = 15.3%. Net debt end 2025 39,380 - 9,852 - 253 = 29,275. Goodwill added 54,832 - 45,853 = 8,979 (end 2024 to June 2026). Specialty Diagnostics best annual margin 910 / 3,339 = 27.3% (2016). Intersegment shares 2025: 201 / 7,554 = 2.7%, 72 / 4,676 = 1.5%, 167 / 23,984 = 0.7%. COVID response less testing 2021: 9.23 - 7.26 = 1.97 billion. Buyback gain 675.00 / 482.66 - 1 = 40%. Olink goodwill 2,301 / 3,146 = 73%. Life Sciences acquisitions 1,342 + 1,864 + 3,146 + 3,870 = 10,222; segment revenue 10,374 - 4,774 = 5,600. Instrumentation market (92.53 / 63.4)^(1/6) - 1 = 6.5%. Healthcare channel 1,788 / 4,676 = 38%. LPBS segment income Q2 936 / 825 - 1 = 13.5%. Interest cover 7,746 / 1,419 = 5.5 times. EPS 17.74 / 4.92 = 3.6 times. One-point price cut 7,440 x 1% = 74, / 3,350 = 2.2%. Laboratory products 2,407 - 2,525 = -118. Clinical diagnostics Q2 290 / 276 - 1 = 5.1%. Revenue 44,556 - 32,218 = 12,338 (2020-2025). Healthcare channel 1,764 / 1,712 - 1 = 3.0% (2024). Tax at 11.5% instead of 7.5%: 7,308 x 4% = 292. Microbiology Q2 166 / 159 - 1 = 4.4%. Pharma services 6,685 / 6,806 - 1 = -1.8% (2024). Clinical diagnostics 1,115 / 4,676 = 23.8%. Revenue per employee 20,918 / 70,000 = about $299,000 (2017); 25,542 / 75,000 = about $341,000 (2019). Research and safety channel 7,019 / 6,841 - 1 = 2.6% (2024), 7,440 / 7,019 - 1 = 6.0% (2025). Backlog 7,768 / 5,087 - 1 = 52.7% (2019). Restructuring 362 / 7,746 = 4.7%. Laboratory products Q2 608 / 601 - 1 = 1.2%. Services 18,592 / 17,614 - 1 = 5.6%, cost of services 12,913 / 12,589 - 1 = 2.6% (2023-2025). Life Sciences Solutions internal share (9,977 - 8,545) / 9,977 = 14.4% (2023). Biosciences 4,169 / 10,374 = 40.2%. COVID share 6.63 / 32.218 = 20.6% (2020), 9.23 / 39.211 = 23.5% (2021). R&D 1,397 / 1,337 - 1 = 4.5%. Segment income / total assets 10,109 / 110,343 = 9.2%. ImmunoDiagnostics 912 - 802 = 110; clinical diagnostics 1,115 - 1,104 = 11. Restructuring 459 / 6,859 = 6.7% (2023). Microbiology 645 / 44,556 = 1.4%. Laboratory products 2,613 / 23,041 = 11.3% (2023), 2,407 / 23,984 = 10.0% (2025). Clario 0.45 x 371.5 = about 167, / 9,098 = 1.8%. LPBS capex / segment income 1,005 / 3,350 = 30%; Life Sciences Solutions 152 / 3,768 = 4.0%. Equity / assets 52,686 / 113,174 = 46.6%. Clinical research 7,915 / 44,556 = 17.8%. Eliminations Q2 565 / 501 - 1 = 12.8%. Instruments 7,301 / 6,292 - 1 = 16.0%. Revenue per employee 18,274 / 55,000 = about $332,000 (2016). Healthcare channel 1,788 / 44,556 = 4.0%. China 2,797 / 32,218 = 8.7% (2020). RPO 29.70 - 27.92 = 1.78 billion - segment margins, shares and growth. — 2015-2026 · publ. September 2026 · source ↗
    Method: Arithmetic on figures reported in Thermo Fisher's Forms 10-K and 10-Q, results releases, earnings calls, MarketsandMarkets and market data; operands shown in the source line.
  10. ReportedIt then recovered to $7,463 million in 2024.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - financial statements: income, cash flow, repurchases, debt and equity. — FY2025 · publ. 26 February 2026 · source ↗
  11. Moat Explorer calcProfitability peaked in 2023 at 26.3%.
    Moat Explorer calculation from Thermo Fisher's reported financial statements, results releases, earnings calls and market data ($ millions unless stated). Revenue by type: consumables + services share (18,664 + 18,592) / 44,556 = 83.6% (2025); (12,576 + 5,490) / 24,358 = 74.2% (2018); (13,109 + 6,046) / 25,542 = 75.0% (2019); (18,527 + 6,912) / 32,218 = 79.0% (2020); (22,608 + 8,850) / 39,211 = 80.2% (2021); (20,624 + 16,367) / 44,915 = 82.4% (2022); (17,597 + 17,614) / 42,857 = 82.2% (2023); (17,587 + 17,845) / 42,879 = 82.6% (2024); H1 2026 (9,794 + 9,899) / 22,999 = 85.6%. Instruments 7,301 / 7,924 - 1 = -7.9% (2022-2025), a fall of 623. Consumables 18,664 / 17,587 - 1 = 6.1%. Services 18,592 / 17,845 - 1 = 4.2%. Gross margin by type 2025: products (25,965 - 13,405) / 25,965 = 48.4%; services (18,592 - 12,913) / 18,592 = 30.5%; total (44,556 - 13,405 - 12,913) / 44,556 = 40.9%. Businesses: BioProduction 2,652 / 2,923 - 1 = -9.3% (2024), 3,200 / 2,652 - 1 = 20.7% (2025), Q2 2026 941 / 745 - 1 = 26.3%. Biosciences 4,169 / 4,238 - 1 = -1.6%. Transplant 492 / 393 - 1 = 25.2%, Q2 134 / 124 - 1 = 8.1%. ImmunoDiagnostics 912 / 802 - 1 = 13.7%, Q2 248 / 234 - 1 = 6.0%. Clinical diagnostics 1,115 / 1,104 - 1 = 1.0%. Microbiology 645 / 618 - 1 = 4.4% (about 2.2% a year); sale price 1,075 / 645 = 1.7 times; microbiology / Specialty Diagnostics 645 / 4,676 = 13.8%. Research and safety channel 7,440 / 6,841 - 1 = 8.8%, Q2 2,036 / 1,883 - 1 = 8.1%, 7,440 - 6,841 = 599. Healthcare channel 1,788 / 1,712 - 1 = 4.4%, 1,788 / 1,764 - 1 = 1.4% (2025), Q2 442 / 407 - 1 = 8.6%. Laboratory products 2,407 / 2,613 - 1 = -7.9%. Channels (7,440 + 1,788) / 44,556 = 9,228 / 44,556 = 20.7%. Revenue growth: 44,556 / 42,879 - 1 = 3.9% (2025), increase 44,556 - 42,879 = 1,677; 44,556 / 42,857 - 1 = 4.0% (2023-2025); 44,556 / 16,965 = 2.6 times (2015-2025). Research channel share of the increase 422 / 1,677 = 25%. Eliminations / revenue 633 / 16,965 = 3.7% (2015), 2,033 / 44,556 = 4.6% (2025). Life Sciences Solutions sold to other segments 1,593 / 10,374 = 15.4%; external revenue 8,781 / 8,160 - 1 = 7.6%. Pharma services 7,142 / 6,685 - 1 = 6.8%; clinical research 7,915 / 7,836 - 1 = 1.0%; Q2 2026 clinical research 2,396 / 1,955 - 1 = 22.6%. Clinical research + pharma services 7,915 + 7,142 = 15,057, / 44,556 = 33.8% (2025); (7,836 + 6,685) / 42,879 = 33.9% (2024); (7,691 + 6,806) / 42,857 = 33.8% (2023); Q2 2026 2,396 + 1,893 = 4,289, / 11,994 = 35.8%; Q2 2025 1,955 + 1,794 = 3,749. Patheon + PPD + Clario 7,358 + 16,036 + 9,098 = 32,492. Clario price / 2025 revenue 9,098 / 1,500 = 6.1 times; 9,098 / 1,250 = 7.3 times; goodwill 5,934 / 9,098 = 65%. Filtration 3,870 / 750 = 5.2 times. LPBS capital expenditure 1,005 / 1,525 = 65.9%. Revenue per employee 32,218 / 80,000 = about $403,000 (2020); 44,556 / 125,000 = about $356,000 (2025); 356 / 403 - 1 = -12%. Remaining performance obligations 24.61 / 28.30 - 1 = -13.0% (2021-2024); 29.70 / 46.336 = 64% of trailing revenue. 2019 backlog 4,577 / 7,768 = 59%. Trailing twelve months to June 2026: revenue 44,556 - 21,219 + 22,999 = 46,336; net income 6,704 - 3,124 + 3,387 = 6,967. COVID: Life Sciences Solutions segment income 3,420 / 7,817 - 1 = -56%; testing 0.33 / 7.26 = 4.5% remaining. Tax rate 547 / 7,308 = 7.5% (2025); 657 / 7,037 = 9.3% (2024); 284 / 6,298 = 4.5% (2023). R&D 1,397 / 44,556 = 3.1%. Adjusted less GAAP EPS 22.87 - 17.74 = 5.13. Acquisitions booked since 2021: PPD 16,036 + PeproTech 1,864 + European viral vector 830 + Mesa Biotech 472 + The Binding Site 2,699 + CorEvitas 910 + Olink 3,146 + filtration and separation 3,870 + Clario 9,098 = 38,925. Goodwill and intangibles / total assets (54,832 + 18,606) / 113,174 = 73,438 / 113,174 = 65% (June 2026); (49,362 + 15,838) / 110,343 = 59% (end 2025). Genetic sciences 2,870 / 2,787 - 1 = 3.0%. Analytical Instruments 7,554 / 63,400 = 11.9% of the MarketsandMarkets estimate; revenue 7,463 / 7,263 - 1 = 2.8% (2024), 7,554 / 7,463 - 1 = 1.2% (2025), Q2 1,847 / 1,728 - 1 = 6.9%. Market value against Danaher 249.58 / 157.81 - 1 = 58%. China share of revenue 2,060 / 20,918 = 9.8% (2017), 2,752 / 25,542 = 10.8% (2019), 3,444 / 39,211 = 8.8% (2021), 3,793 / 44,915 = 8.4% (2022). Year-end P/E = market value / net income: 56.61 / 1.975 = 28.7 (2015), 55.74 / 2.022 = 27.6 (2016), 76.14 / 2.225 = 34.2 (2017), 90.09 / 2.938 = 30.7 (2018), 130.27 / 3.696 = 35.2 (2019), 184.61 / 6.375 = 29.0 (2020), 262.92 / 7.725 = 34.0 (2021), 215.98 / 6.950 = 31.1 (2022), 205.08 / 5.995 = 34.2 (2023), 198.99 / 6.335 = 31.4 (2024), 217.70 / 6.704 = 32.5 (2025), trailing 249.58 / 6.967 = 35.8. Segment margins = segment income / segment revenue: Life Sciences Solutions 1,414 / 4,774 = 29.6% (2015), 2,446 / 6,856 = 35.7% (2019), 7,817 / 15,631 = 50.0% (2021), 3,420 / 9,977 = 34.3% (2023), 3,503 / 9,631 = 36.4% (2024); Analytical Instruments 613 / 3,208 = 19.1% (2015), 1,027 / 4,821 = 21.3% (2017), 1,273 / 5,522 = 23.1% (2019), 808 / 5,124 = 15.8% (2020), 1,908 / 7,263 = 26.3% (2023); Specialty Diagnostics 873 / 3,244 = 26.9% (2015), 1,024 / 4,763 = 21.5% (2022); LPBS 922 / 6,372 = 14.5% (2015), 1,271 / 12,245 = 10.4% (2020), 1,844 / 14,862 = 12.4% (2021), 2,872 / 22,511 = 12.8% (2022), 3,358 / 23,041 = 14.6% (2023), 3,090 / 23,157 = 13.3% (2024). Segment shares 2025: Life Sciences Solutions income 3,768 / 10,109 = 37.3%, revenue 10,374 / 46,589 = 22.3%; LPBS external revenue 23,818 / 44,556 = 53.5%. Combined segment margin 10,109 / (44,556 + 2,033) = 10,109 / 46,589 = 21.7%. Segment growth: Life Sciences Solutions 10,374 / 9,631 - 1 = 7.7% (2025), Q2 2026 2,815 / 2,499 - 1 = 12.6%; Specialty Diagnostics 4,676 / 4,512 - 1 = 3.6% (2025), Q2 1,205 / 1,134 - 1 = 6.3%; LPBS 23,984 / 23,157 - 1 = 3.6% (2025), Q2 6,693 / 5,995 - 1 = 11.6%. Ten-year compound growth 2015-2025: Life Sciences Solutions (10,374 / 4,774)^(1/10) - 1 = 8.1%; Specialty Diagnostics (4,676 / 3,244)^(1/10) - 1 = 3.7%; LPBS (23,984 / 6,372)^(1/10) - 1 = 14.2%. Additional: return on equity 6,704 / ((53,407 + 49,584) / 2) = 13.0% (2025). Instruments share 6,292 / 24,358 = 25.8% (2018), 3,305 / 22,999 = 14.4% (H1 2026). Life Sciences Solutions segment income Q2 1,041 / 919 - 1 = 13.3%. Services share 2,297 / 16,965 = 13.5% (2015), 18,592 / 44,556 = 41.7% (2025). Service gross margin (17,614 - 12,589) / 17,614 = 28.5% (2023), (17,845 - 12,654) / 17,845 = 29.1% (2024); product (25,034 - 12,523) / 25,034 = 50.0% (2024). LPBS growth 23,984 - 23,157 = 827 = 457 + 422 - 118 (laboratory products) + 79 (clinical research) - 13 (eliminations). Eliminations 3,010 / 39,211 = 7.7% (2021). Europe 11,826 / 10,741 - 1 = 10.1%; North America 23,033 / 22,764 - 1 = 1.2% (2023-2025). Headcount 125,000 / 122,000 - 1 = 2.5%. Electron microscopy 2,957 / 2,564 - 1 = 15.3%. Net debt end 2025 39,380 - 9,852 - 253 = 29,275. Goodwill added 54,832 - 45,853 = 8,979 (end 2024 to June 2026). Specialty Diagnostics best annual margin 910 / 3,339 = 27.3% (2016). Intersegment shares 2025: 201 / 7,554 = 2.7%, 72 / 4,676 = 1.5%, 167 / 23,984 = 0.7%. COVID response less testing 2021: 9.23 - 7.26 = 1.97 billion. Buyback gain 675.00 / 482.66 - 1 = 40%. Olink goodwill 2,301 / 3,146 = 73%. Life Sciences acquisitions 1,342 + 1,864 + 3,146 + 3,870 = 10,222; segment revenue 10,374 - 4,774 = 5,600. Instrumentation market (92.53 / 63.4)^(1/6) - 1 = 6.5%. Healthcare channel 1,788 / 4,676 = 38%. LPBS segment income Q2 936 / 825 - 1 = 13.5%. Interest cover 7,746 / 1,419 = 5.5 times. EPS 17.74 / 4.92 = 3.6 times. One-point price cut 7,440 x 1% = 74, / 3,350 = 2.2%. Laboratory products 2,407 - 2,525 = -118. Clinical diagnostics Q2 290 / 276 - 1 = 5.1%. Revenue 44,556 - 32,218 = 12,338 (2020-2025). Healthcare channel 1,764 / 1,712 - 1 = 3.0% (2024). Tax at 11.5% instead of 7.5%: 7,308 x 4% = 292. Microbiology Q2 166 / 159 - 1 = 4.4%. Pharma services 6,685 / 6,806 - 1 = -1.8% (2024). Clinical diagnostics 1,115 / 4,676 = 23.8%. Revenue per employee 20,918 / 70,000 = about $299,000 (2017); 25,542 / 75,000 = about $341,000 (2019). Research and safety channel 7,019 / 6,841 - 1 = 2.6% (2024), 7,440 / 7,019 - 1 = 6.0% (2025). Backlog 7,768 / 5,087 - 1 = 52.7% (2019). Restructuring 362 / 7,746 = 4.7%. Laboratory products Q2 608 / 601 - 1 = 1.2%. Services 18,592 / 17,614 - 1 = 5.6%, cost of services 12,913 / 12,589 - 1 = 2.6% (2023-2025). Life Sciences Solutions internal share (9,977 - 8,545) / 9,977 = 14.4% (2023). Biosciences 4,169 / 10,374 = 40.2%. COVID share 6.63 / 32.218 = 20.6% (2020), 9.23 / 39.211 = 23.5% (2021). R&D 1,397 / 1,337 - 1 = 4.5%. Segment income / total assets 10,109 / 110,343 = 9.2%. ImmunoDiagnostics 912 - 802 = 110; clinical diagnostics 1,115 - 1,104 = 11. Restructuring 459 / 6,859 = 6.7% (2023). Microbiology 645 / 44,556 = 1.4%. Laboratory products 2,613 / 23,041 = 11.3% (2023), 2,407 / 23,984 = 10.0% (2025). Clario 0.45 x 371.5 = about 167, / 9,098 = 1.8%. LPBS capex / segment income 1,005 / 3,350 = 30%; Life Sciences Solutions 152 / 3,768 = 4.0%. Equity / assets 52,686 / 113,174 = 46.6%. Clinical research 7,915 / 44,556 = 17.8%. Eliminations Q2 565 / 501 - 1 = 12.8%. Instruments 7,301 / 6,292 - 1 = 16.0%. Revenue per employee 18,274 / 55,000 = about $332,000 (2016). Healthcare channel 1,788 / 44,556 = 4.0%. China 2,797 / 32,218 = 8.7% (2020). RPO 29.70 - 27.92 = 1.78 billion - revenue by type, company growth, backlog and other ratios. — 2015-2026 · publ. September 2026 · source ↗
    Method: Arithmetic on figures reported in Thermo Fisher's Forms 10-K and 10-Q, results releases, earnings calls, MarketsandMarkets and market data; operands shown in the source line.
  12. ReportedIn 2025 the 10-K attributed the fall to "the impacts of tariffs and related foreign exchange, strategic investments, and unfavorable business mix".
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - Item 1A risk factors and competition. — FY2025 · publ. 26 February 2026 · source ↗
  13. ReportedIn the second quarter of 2026 the margin was 23.0% against 18.8% a year earlier.
    Thermo Fisher Scientific second-quarter 2026 results, Form 8-K exhibit 99.1 - revenue, organic growth, segment income and margins, free cash flow and the balance sheet. — Q2 2026 · publ. 23 July 2026 · source ↗
  14. Moat Explorer calcRevenue rose 2.8% in 2024 and 1.2% in 2025, with chemical analysis down $78 million and electron microscopy up from $2,870 million to $2,957 million.
    Moat Explorer calculation from Thermo Fisher's reported financial statements, results releases, earnings calls and market data ($ millions unless stated). Revenue by type: consumables + services share (18,664 + 18,592) / 44,556 = 83.6% (2025); (12,576 + 5,490) / 24,358 = 74.2% (2018); (13,109 + 6,046) / 25,542 = 75.0% (2019); (18,527 + 6,912) / 32,218 = 79.0% (2020); (22,608 + 8,850) / 39,211 = 80.2% (2021); (20,624 + 16,367) / 44,915 = 82.4% (2022); (17,597 + 17,614) / 42,857 = 82.2% (2023); (17,587 + 17,845) / 42,879 = 82.6% (2024); H1 2026 (9,794 + 9,899) / 22,999 = 85.6%. Instruments 7,301 / 7,924 - 1 = -7.9% (2022-2025), a fall of 623. Consumables 18,664 / 17,587 - 1 = 6.1%. Services 18,592 / 17,845 - 1 = 4.2%. Gross margin by type 2025: products (25,965 - 13,405) / 25,965 = 48.4%; services (18,592 - 12,913) / 18,592 = 30.5%; total (44,556 - 13,405 - 12,913) / 44,556 = 40.9%. Businesses: BioProduction 2,652 / 2,923 - 1 = -9.3% (2024), 3,200 / 2,652 - 1 = 20.7% (2025), Q2 2026 941 / 745 - 1 = 26.3%. Biosciences 4,169 / 4,238 - 1 = -1.6%. Transplant 492 / 393 - 1 = 25.2%, Q2 134 / 124 - 1 = 8.1%. ImmunoDiagnostics 912 / 802 - 1 = 13.7%, Q2 248 / 234 - 1 = 6.0%. Clinical diagnostics 1,115 / 1,104 - 1 = 1.0%. Microbiology 645 / 618 - 1 = 4.4% (about 2.2% a year); sale price 1,075 / 645 = 1.7 times; microbiology / Specialty Diagnostics 645 / 4,676 = 13.8%. Research and safety channel 7,440 / 6,841 - 1 = 8.8%, Q2 2,036 / 1,883 - 1 = 8.1%, 7,440 - 6,841 = 599. Healthcare channel 1,788 / 1,712 - 1 = 4.4%, 1,788 / 1,764 - 1 = 1.4% (2025), Q2 442 / 407 - 1 = 8.6%. Laboratory products 2,407 / 2,613 - 1 = -7.9%. Channels (7,440 + 1,788) / 44,556 = 9,228 / 44,556 = 20.7%. Revenue growth: 44,556 / 42,879 - 1 = 3.9% (2025), increase 44,556 - 42,879 = 1,677; 44,556 / 42,857 - 1 = 4.0% (2023-2025); 44,556 / 16,965 = 2.6 times (2015-2025). Research channel share of the increase 422 / 1,677 = 25%. Eliminations / revenue 633 / 16,965 = 3.7% (2015), 2,033 / 44,556 = 4.6% (2025). Life Sciences Solutions sold to other segments 1,593 / 10,374 = 15.4%; external revenue 8,781 / 8,160 - 1 = 7.6%. Pharma services 7,142 / 6,685 - 1 = 6.8%; clinical research 7,915 / 7,836 - 1 = 1.0%; Q2 2026 clinical research 2,396 / 1,955 - 1 = 22.6%. Clinical research + pharma services 7,915 + 7,142 = 15,057, / 44,556 = 33.8% (2025); (7,836 + 6,685) / 42,879 = 33.9% (2024); (7,691 + 6,806) / 42,857 = 33.8% (2023); Q2 2026 2,396 + 1,893 = 4,289, / 11,994 = 35.8%; Q2 2025 1,955 + 1,794 = 3,749. Patheon + PPD + Clario 7,358 + 16,036 + 9,098 = 32,492. Clario price / 2025 revenue 9,098 / 1,500 = 6.1 times; 9,098 / 1,250 = 7.3 times; goodwill 5,934 / 9,098 = 65%. Filtration 3,870 / 750 = 5.2 times. LPBS capital expenditure 1,005 / 1,525 = 65.9%. Revenue per employee 32,218 / 80,000 = about $403,000 (2020); 44,556 / 125,000 = about $356,000 (2025); 356 / 403 - 1 = -12%. Remaining performance obligations 24.61 / 28.30 - 1 = -13.0% (2021-2024); 29.70 / 46.336 = 64% of trailing revenue. 2019 backlog 4,577 / 7,768 = 59%. Trailing twelve months to June 2026: revenue 44,556 - 21,219 + 22,999 = 46,336; net income 6,704 - 3,124 + 3,387 = 6,967. COVID: Life Sciences Solutions segment income 3,420 / 7,817 - 1 = -56%; testing 0.33 / 7.26 = 4.5% remaining. Tax rate 547 / 7,308 = 7.5% (2025); 657 / 7,037 = 9.3% (2024); 284 / 6,298 = 4.5% (2023). R&D 1,397 / 44,556 = 3.1%. Adjusted less GAAP EPS 22.87 - 17.74 = 5.13. Acquisitions booked since 2021: PPD 16,036 + PeproTech 1,864 + European viral vector 830 + Mesa Biotech 472 + The Binding Site 2,699 + CorEvitas 910 + Olink 3,146 + filtration and separation 3,870 + Clario 9,098 = 38,925. Goodwill and intangibles / total assets (54,832 + 18,606) / 113,174 = 73,438 / 113,174 = 65% (June 2026); (49,362 + 15,838) / 110,343 = 59% (end 2025). Genetic sciences 2,870 / 2,787 - 1 = 3.0%. Analytical Instruments 7,554 / 63,400 = 11.9% of the MarketsandMarkets estimate; revenue 7,463 / 7,263 - 1 = 2.8% (2024), 7,554 / 7,463 - 1 = 1.2% (2025), Q2 1,847 / 1,728 - 1 = 6.9%. Market value against Danaher 249.58 / 157.81 - 1 = 58%. China share of revenue 2,060 / 20,918 = 9.8% (2017), 2,752 / 25,542 = 10.8% (2019), 3,444 / 39,211 = 8.8% (2021), 3,793 / 44,915 = 8.4% (2022). Year-end P/E = market value / net income: 56.61 / 1.975 = 28.7 (2015), 55.74 / 2.022 = 27.6 (2016), 76.14 / 2.225 = 34.2 (2017), 90.09 / 2.938 = 30.7 (2018), 130.27 / 3.696 = 35.2 (2019), 184.61 / 6.375 = 29.0 (2020), 262.92 / 7.725 = 34.0 (2021), 215.98 / 6.950 = 31.1 (2022), 205.08 / 5.995 = 34.2 (2023), 198.99 / 6.335 = 31.4 (2024), 217.70 / 6.704 = 32.5 (2025), trailing 249.58 / 6.967 = 35.8. Segment margins = segment income / segment revenue: Life Sciences Solutions 1,414 / 4,774 = 29.6% (2015), 2,446 / 6,856 = 35.7% (2019), 7,817 / 15,631 = 50.0% (2021), 3,420 / 9,977 = 34.3% (2023), 3,503 / 9,631 = 36.4% (2024); Analytical Instruments 613 / 3,208 = 19.1% (2015), 1,027 / 4,821 = 21.3% (2017), 1,273 / 5,522 = 23.1% (2019), 808 / 5,124 = 15.8% (2020), 1,908 / 7,263 = 26.3% (2023); Specialty Diagnostics 873 / 3,244 = 26.9% (2015), 1,024 / 4,763 = 21.5% (2022); LPBS 922 / 6,372 = 14.5% (2015), 1,271 / 12,245 = 10.4% (2020), 1,844 / 14,862 = 12.4% (2021), 2,872 / 22,511 = 12.8% (2022), 3,358 / 23,041 = 14.6% (2023), 3,090 / 23,157 = 13.3% (2024). Segment shares 2025: Life Sciences Solutions income 3,768 / 10,109 = 37.3%, revenue 10,374 / 46,589 = 22.3%; LPBS external revenue 23,818 / 44,556 = 53.5%. Combined segment margin 10,109 / (44,556 + 2,033) = 10,109 / 46,589 = 21.7%. Segment growth: Life Sciences Solutions 10,374 / 9,631 - 1 = 7.7% (2025), Q2 2026 2,815 / 2,499 - 1 = 12.6%; Specialty Diagnostics 4,676 / 4,512 - 1 = 3.6% (2025), Q2 1,205 / 1,134 - 1 = 6.3%; LPBS 23,984 / 23,157 - 1 = 3.6% (2025), Q2 6,693 / 5,995 - 1 = 11.6%. Ten-year compound growth 2015-2025: Life Sciences Solutions (10,374 / 4,774)^(1/10) - 1 = 8.1%; Specialty Diagnostics (4,676 / 3,244)^(1/10) - 1 = 3.7%; LPBS (23,984 / 6,372)^(1/10) - 1 = 14.2%. Additional: return on equity 6,704 / ((53,407 + 49,584) / 2) = 13.0% (2025). Instruments share 6,292 / 24,358 = 25.8% (2018), 3,305 / 22,999 = 14.4% (H1 2026). Life Sciences Solutions segment income Q2 1,041 / 919 - 1 = 13.3%. Services share 2,297 / 16,965 = 13.5% (2015), 18,592 / 44,556 = 41.7% (2025). Service gross margin (17,614 - 12,589) / 17,614 = 28.5% (2023), (17,845 - 12,654) / 17,845 = 29.1% (2024); product (25,034 - 12,523) / 25,034 = 50.0% (2024). LPBS growth 23,984 - 23,157 = 827 = 457 + 422 - 118 (laboratory products) + 79 (clinical research) - 13 (eliminations). Eliminations 3,010 / 39,211 = 7.7% (2021). Europe 11,826 / 10,741 - 1 = 10.1%; North America 23,033 / 22,764 - 1 = 1.2% (2023-2025). Headcount 125,000 / 122,000 - 1 = 2.5%. Electron microscopy 2,957 / 2,564 - 1 = 15.3%. Net debt end 2025 39,380 - 9,852 - 253 = 29,275. Goodwill added 54,832 - 45,853 = 8,979 (end 2024 to June 2026). Specialty Diagnostics best annual margin 910 / 3,339 = 27.3% (2016). Intersegment shares 2025: 201 / 7,554 = 2.7%, 72 / 4,676 = 1.5%, 167 / 23,984 = 0.7%. COVID response less testing 2021: 9.23 - 7.26 = 1.97 billion. Buyback gain 675.00 / 482.66 - 1 = 40%. Olink goodwill 2,301 / 3,146 = 73%. Life Sciences acquisitions 1,342 + 1,864 + 3,146 + 3,870 = 10,222; segment revenue 10,374 - 4,774 = 5,600. Instrumentation market (92.53 / 63.4)^(1/6) - 1 = 6.5%. Healthcare channel 1,788 / 4,676 = 38%. LPBS segment income Q2 936 / 825 - 1 = 13.5%. Interest cover 7,746 / 1,419 = 5.5 times. EPS 17.74 / 4.92 = 3.6 times. One-point price cut 7,440 x 1% = 74, / 3,350 = 2.2%. Laboratory products 2,407 - 2,525 = -118. Clinical diagnostics Q2 290 / 276 - 1 = 5.1%. Revenue 44,556 - 32,218 = 12,338 (2020-2025). Healthcare channel 1,764 / 1,712 - 1 = 3.0% (2024). Tax at 11.5% instead of 7.5%: 7,308 x 4% = 292. Microbiology Q2 166 / 159 - 1 = 4.4%. Pharma services 6,685 / 6,806 - 1 = -1.8% (2024). Clinical diagnostics 1,115 / 4,676 = 23.8%. Revenue per employee 20,918 / 70,000 = about $299,000 (2017); 25,542 / 75,000 = about $341,000 (2019). Research and safety channel 7,019 / 6,841 - 1 = 2.6% (2024), 7,440 / 7,019 - 1 = 6.0% (2025). Backlog 7,768 / 5,087 - 1 = 52.7% (2019). Restructuring 362 / 7,746 = 4.7%. Laboratory products Q2 608 / 601 - 1 = 1.2%. Services 18,592 / 17,614 - 1 = 5.6%, cost of services 12,913 / 12,589 - 1 = 2.6% (2023-2025). Life Sciences Solutions internal share (9,977 - 8,545) / 9,977 = 14.4% (2023). Biosciences 4,169 / 10,374 = 40.2%. COVID share 6.63 / 32.218 = 20.6% (2020), 9.23 / 39.211 = 23.5% (2021). R&D 1,397 / 1,337 - 1 = 4.5%. Segment income / total assets 10,109 / 110,343 = 9.2%. ImmunoDiagnostics 912 - 802 = 110; clinical diagnostics 1,115 - 1,104 = 11. Restructuring 459 / 6,859 = 6.7% (2023). Microbiology 645 / 44,556 = 1.4%. Laboratory products 2,613 / 23,041 = 11.3% (2023), 2,407 / 23,984 = 10.0% (2025). Clario 0.45 x 371.5 = about 167, / 9,098 = 1.8%. LPBS capex / segment income 1,005 / 3,350 = 30%; Life Sciences Solutions 152 / 3,768 = 4.0%. Equity / assets 52,686 / 113,174 = 46.6%. Clinical research 7,915 / 44,556 = 17.8%. Eliminations Q2 565 / 501 - 1 = 12.8%. Instruments 7,301 / 6,292 - 1 = 16.0%. Revenue per employee 18,274 / 55,000 = about $332,000 (2016). Healthcare channel 1,788 / 44,556 = 4.0%. China 2,797 / 32,218 = 8.7% (2020). RPO 29.70 - 27.92 = 1.78 billion - revenue by business: growth and shares. — 2015-2026 · publ. September 2026 · source ↗
    Method: Arithmetic on figures reported in Thermo Fisher's Forms 10-K and 10-Q, results releases, earnings calls, MarketsandMarkets and market data; operands shown in the source line.
  15. ReportedRevenue rose 2.8% in 2024 and 1.2% in 2025, with chemical analysis down $78 million and electron microscopy up from $2,870 million to $2,957 million.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - revenue by business. — FY2025 · publ. 26 February 2026 · source ↗
  16. ReportedRevenue rose 2.8% in 2024 and 1.2% in 2025, with chemical analysis down $78 million and electron microscopy up from $2,870 million to $2,957 million.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - revenue by business. — FY2025 · publ. 26 February 2026 · source ↗
  17. ReportedThe second quarter of 2026 was better: revenue of $1,847 million against $1,728 million, and 7% organic growth.
    Thermo Fisher Scientific second-quarter 2026 results, Form 8-K exhibit 99.1 - revenue, organic growth, segment income and margins, free cash flow and the balance sheet. — Q2 2026 · publ. 23 July 2026 · source ↗
  18. ReportedThe second quarter of 2026 was better: revenue of $1,847 million against $1,728 million, and 7% organic growth.
    Thermo Fisher Scientific second-quarter 2026 earnings call transcript (Motley Fool) - organic growth by segment and market, China, the raised 2026 guidance, leverage, adjusted ROIC and the microbiology sale. Figures from the transcript body, not the summary block - 2026 guidance, capital deployment, leverage and adjusted ROIC. — Q2 2026 · publ. 23 July 2026 · source ↗
  19. ReportedIn the second quarter of 2026 chromatography and mass spectrometry revenue was $821 million against $784 million, chemical analysis $318 million against $292 million and electron microscopy $707 million against $652 million.
    Thermo Fisher Scientific Form 10-Q for the quarter ended 27 June 2026 - revenue by business and by type, the Clario purchase price, the microbiology sale, share repurchases, dividends and the balance sheet. — Q2 2026 · publ. 31 July 2026 · source ↗
  20. ReportedSegment income was $424 million against $325 million.
    Thermo Fisher Scientific second-quarter 2026 results, Form 8-K exhibit 99.1 - revenue, organic growth, segment income and margins, free cash flow and the balance sheet. — Q2 2026 · publ. 23 July 2026 · source ↗
  21. ReportedThe segment spent $124 million on capital equipment in 2025, a small figure for a company that makes the machines others buy.
    Thermo Fisher Scientific Form 10-K for fiscal 2025 - segment information: revenue, income, margins, assets and capital spending. — FY2025 · publ. 26 February 2026 · source ↗
  22. ReportedFEI was paid for in cash, $4,440 million, and electron microscopy has been the segment's fastest-growing business over the past two years.
    Thermo Fisher Scientific Form 10-K for fiscal 2017 - segment revenue and income for 2015-2017, net income and EPS, service revenue, headcount and the FEI, Affymetrix and Patheon acquisitions. — FY2017 · publ. February 2018 · source ↗
  23. Third-party estimateMarketsandMarkets expects the instrumentation market to grow from USD 63.4 billion in 2025 to USD 92.53 billion by 2031, about 6.5% a year; a third-party estimate, but faster than the segment's recent growth.
    MarketsandMarkets research insight on life-science instrumentation - leading participants and a market estimate of USD 63.4 billion in 2025 rising to USD 92.53 billion by 2031. — 2025 · publ. 2025 · source ↗
  24. Moat Explorer calcMarketsandMarkets expects the instrumentation market to grow from USD 63.4 billion in 2025 to USD 92.53 billion by 2031, about 6.5% a year; a third-party estimate, but faster than the segment's recent growth.
    Moat Explorer calculation from Thermo Fisher's reported financial statements, results releases, earnings calls and market data ($ millions unless stated). Revenue by type: consumables + services share (18,664 + 18,592) / 44,556 = 83.6% (2025); (12,576 + 5,490) / 24,358 = 74.2% (2018); (13,109 + 6,046) / 25,542 = 75.0% (2019); (18,527 + 6,912) / 32,218 = 79.0% (2020); (22,608 + 8,850) / 39,211 = 80.2% (2021); (20,624 + 16,367) / 44,915 = 82.4% (2022); (17,597 + 17,614) / 42,857 = 82.2% (2023); (17,587 + 17,845) / 42,879 = 82.6% (2024); H1 2026 (9,794 + 9,899) / 22,999 = 85.6%. Instruments 7,301 / 7,924 - 1 = -7.9% (2022-2025), a fall of 623. Consumables 18,664 / 17,587 - 1 = 6.1%. Services 18,592 / 17,845 - 1 = 4.2%. Gross margin by type 2025: products (25,965 - 13,405) / 25,965 = 48.4%; services (18,592 - 12,913) / 18,592 = 30.5%; total (44,556 - 13,405 - 12,913) / 44,556 = 40.9%. Businesses: BioProduction 2,652 / 2,923 - 1 = -9.3% (2024), 3,200 / 2,652 - 1 = 20.7% (2025), Q2 2026 941 / 745 - 1 = 26.3%. Biosciences 4,169 / 4,238 - 1 = -1.6%. Transplant 492 / 393 - 1 = 25.2%, Q2 134 / 124 - 1 = 8.1%. ImmunoDiagnostics 912 / 802 - 1 = 13.7%, Q2 248 / 234 - 1 = 6.0%. Clinical diagnostics 1,115 / 1,104 - 1 = 1.0%. Microbiology 645 / 618 - 1 = 4.4% (about 2.2% a year); sale price 1,075 / 645 = 1.7 times; microbiology / Specialty Diagnostics 645 / 4,676 = 13.8%. Research and safety channel 7,440 / 6,841 - 1 = 8.8%, Q2 2,036 / 1,883 - 1 = 8.1%, 7,440 - 6,841 = 599. Healthcare channel 1,788 / 1,712 - 1 = 4.4%, 1,788 / 1,764 - 1 = 1.4% (2025), Q2 442 / 407 - 1 = 8.6%. Laboratory products 2,407 / 2,613 - 1 = -7.9%. Channels (7,440 + 1,788) / 44,556 = 9,228 / 44,556 = 20.7%. Revenue growth: 44,556 / 42,879 - 1 = 3.9% (2025), increase 44,556 - 42,879 = 1,677; 44,556 / 42,857 - 1 = 4.0% (2023-2025); 44,556 / 16,965 = 2.6 times (2015-2025). Research channel share of the increase 422 / 1,677 = 25%. Eliminations / revenue 633 / 16,965 = 3.7% (2015), 2,033 / 44,556 = 4.6% (2025). Life Sciences Solutions sold to other segments 1,593 / 10,374 = 15.4%; external revenue 8,781 / 8,160 - 1 = 7.6%. Pharma services 7,142 / 6,685 - 1 = 6.8%; clinical research 7,915 / 7,836 - 1 = 1.0%; Q2 2026 clinical research 2,396 / 1,955 - 1 = 22.6%. Clinical research + pharma services 7,915 + 7,142 = 15,057, / 44,556 = 33.8% (2025); (7,836 + 6,685) / 42,879 = 33.9% (2024); (7,691 + 6,806) / 42,857 = 33.8% (2023); Q2 2026 2,396 + 1,893 = 4,289, / 11,994 = 35.8%; Q2 2025 1,955 + 1,794 = 3,749. Patheon + PPD + Clario 7,358 + 16,036 + 9,098 = 32,492. Clario price / 2025 revenue 9,098 / 1,500 = 6.1 times; 9,098 / 1,250 = 7.3 times; goodwill 5,934 / 9,098 = 65%. Filtration 3,870 / 750 = 5.2 times. LPBS capital expenditure 1,005 / 1,525 = 65.9%. Revenue per employee 32,218 / 80,000 = about $403,000 (2020); 44,556 / 125,000 = about $356,000 (2025); 356 / 403 - 1 = -12%. Remaining performance obligations 24.61 / 28.30 - 1 = -13.0% (2021-2024); 29.70 / 46.336 = 64% of trailing revenue. 2019 backlog 4,577 / 7,768 = 59%. Trailing twelve months to June 2026: revenue 44,556 - 21,219 + 22,999 = 46,336; net income 6,704 - 3,124 + 3,387 = 6,967. COVID: Life Sciences Solutions segment income 3,420 / 7,817 - 1 = -56%; testing 0.33 / 7.26 = 4.5% remaining. Tax rate 547 / 7,308 = 7.5% (2025); 657 / 7,037 = 9.3% (2024); 284 / 6,298 = 4.5% (2023). R&D 1,397 / 44,556 = 3.1%. Adjusted less GAAP EPS 22.87 - 17.74 = 5.13. Acquisitions booked since 2021: PPD 16,036 + PeproTech 1,864 + European viral vector 830 + Mesa Biotech 472 + The Binding Site 2,699 + CorEvitas 910 + Olink 3,146 + filtration and separation 3,870 + Clario 9,098 = 38,925. Goodwill and intangibles / total assets (54,832 + 18,606) / 113,174 = 73,438 / 113,174 = 65% (June 2026); (49,362 + 15,838) / 110,343 = 59% (end 2025). Genetic sciences 2,870 / 2,787 - 1 = 3.0%. Analytical Instruments 7,554 / 63,400 = 11.9% of the MarketsandMarkets estimate; revenue 7,463 / 7,263 - 1 = 2.8% (2024), 7,554 / 7,463 - 1 = 1.2% (2025), Q2 1,847 / 1,728 - 1 = 6.9%. Market value against Danaher 249.58 / 157.81 - 1 = 58%. China share of revenue 2,060 / 20,918 = 9.8% (2017), 2,752 / 25,542 = 10.8% (2019), 3,444 / 39,211 = 8.8% (2021), 3,793 / 44,915 = 8.4% (2022). Year-end P/E = market value / net income: 56.61 / 1.975 = 28.7 (2015), 55.74 / 2.022 = 27.6 (2016), 76.14 / 2.225 = 34.2 (2017), 90.09 / 2.938 = 30.7 (2018), 130.27 / 3.696 = 35.2 (2019), 184.61 / 6.375 = 29.0 (2020), 262.92 / 7.725 = 34.0 (2021), 215.98 / 6.950 = 31.1 (2022), 205.08 / 5.995 = 34.2 (2023), 198.99 / 6.335 = 31.4 (2024), 217.70 / 6.704 = 32.5 (2025), trailing 249.58 / 6.967 = 35.8. Segment margins = segment income / segment revenue: Life Sciences Solutions 1,414 / 4,774 = 29.6% (2015), 2,446 / 6,856 = 35.7% (2019), 7,817 / 15,631 = 50.0% (2021), 3,420 / 9,977 = 34.3% (2023), 3,503 / 9,631 = 36.4% (2024); Analytical Instruments 613 / 3,208 = 19.1% (2015), 1,027 / 4,821 = 21.3% (2017), 1,273 / 5,522 = 23.1% (2019), 808 / 5,124 = 15.8% (2020), 1,908 / 7,263 = 26.3% (2023); Specialty Diagnostics 873 / 3,244 = 26.9% (2015), 1,024 / 4,763 = 21.5% (2022); LPBS 922 / 6,372 = 14.5% (2015), 1,271 / 12,245 = 10.4% (2020), 1,844 / 14,862 = 12.4% (2021), 2,872 / 22,511 = 12.8% (2022), 3,358 / 23,041 = 14.6% (2023), 3,090 / 23,157 = 13.3% (2024). Segment shares 2025: Life Sciences Solutions income 3,768 / 10,109 = 37.3%, revenue 10,374 / 46,589 = 22.3%; LPBS external revenue 23,818 / 44,556 = 53.5%. Combined segment margin 10,109 / (44,556 + 2,033) = 10,109 / 46,589 = 21.7%. Segment growth: Life Sciences Solutions 10,374 / 9,631 - 1 = 7.7% (2025), Q2 2026 2,815 / 2,499 - 1 = 12.6%; Specialty Diagnostics 4,676 / 4,512 - 1 = 3.6% (2025), Q2 1,205 / 1,134 - 1 = 6.3%; LPBS 23,984 / 23,157 - 1 = 3.6% (2025), Q2 6,693 / 5,995 - 1 = 11.6%. Ten-year compound growth 2015-2025: Life Sciences Solutions (10,374 / 4,774)^(1/10) - 1 = 8.1%; Specialty Diagnostics (4,676 / 3,244)^(1/10) - 1 = 3.7%; LPBS (23,984 / 6,372)^(1/10) - 1 = 14.2%. Additional: return on equity 6,704 / ((53,407 + 49,584) / 2) = 13.0% (2025). Instruments share 6,292 / 24,358 = 25.8% (2018), 3,305 / 22,999 = 14.4% (H1 2026). Life Sciences Solutions segment income Q2 1,041 / 919 - 1 = 13.3%. Services share 2,297 / 16,965 = 13.5% (2015), 18,592 / 44,556 = 41.7% (2025). Service gross margin (17,614 - 12,589) / 17,614 = 28.5% (2023), (17,845 - 12,654) / 17,845 = 29.1% (2024); product (25,034 - 12,523) / 25,034 = 50.0% (2024). LPBS growth 23,984 - 23,157 = 827 = 457 + 422 - 118 (laboratory products) + 79 (clinical research) - 13 (eliminations). Eliminations 3,010 / 39,211 = 7.7% (2021). Europe 11,826 / 10,741 - 1 = 10.1%; North America 23,033 / 22,764 - 1 = 1.2% (2023-2025). Headcount 125,000 / 122,000 - 1 = 2.5%. Electron microscopy 2,957 / 2,564 - 1 = 15.3%. Net debt end 2025 39,380 - 9,852 - 253 = 29,275. Goodwill added 54,832 - 45,853 = 8,979 (end 2024 to June 2026). Specialty Diagnostics best annual margin 910 / 3,339 = 27.3% (2016). Intersegment shares 2025: 201 / 7,554 = 2.7%, 72 / 4,676 = 1.5%, 167 / 23,984 = 0.7%. COVID response less testing 2021: 9.23 - 7.26 = 1.97 billion. Buyback gain 675.00 / 482.66 - 1 = 40%. Olink goodwill 2,301 / 3,146 = 73%. Life Sciences acquisitions 1,342 + 1,864 + 3,146 + 3,870 = 10,222; segment revenue 10,374 - 4,774 = 5,600. Instrumentation market (92.53 / 63.4)^(1/6) - 1 = 6.5%. Healthcare channel 1,788 / 4,676 = 38%. LPBS segment income Q2 936 / 825 - 1 = 13.5%. Interest cover 7,746 / 1,419 = 5.5 times. EPS 17.74 / 4.92 = 3.6 times. One-point price cut 7,440 x 1% = 74, / 3,350 = 2.2%. Laboratory products 2,407 - 2,525 = -118. Clinical diagnostics Q2 290 / 276 - 1 = 5.1%. Revenue 44,556 - 32,218 = 12,338 (2020-2025). Healthcare channel 1,764 / 1,712 - 1 = 3.0% (2024). Tax at 11.5% instead of 7.5%: 7,308 x 4% = 292. Microbiology Q2 166 / 159 - 1 = 4.4%. Pharma services 6,685 / 6,806 - 1 = -1.8% (2024). Clinical diagnostics 1,115 / 4,676 = 23.8%. Revenue per employee 20,918 / 70,000 = about $299,000 (2017); 25,542 / 75,000 = about $341,000 (2019). Research and safety channel 7,019 / 6,841 - 1 = 2.6% (2024), 7,440 / 7,019 - 1 = 6.0% (2025). Backlog 7,768 / 5,087 - 1 = 52.7% (2019). Restructuring 362 / 7,746 = 4.7%. Laboratory products Q2 608 / 601 - 1 = 1.2%. Services 18,592 / 17,614 - 1 = 5.6%, cost of services 12,913 / 12,589 - 1 = 2.6% (2023-2025). Life Sciences Solutions internal share (9,977 - 8,545) / 9,977 = 14.4% (2023). Biosciences 4,169 / 10,374 = 40.2%. COVID share 6.63 / 32.218 = 20.6% (2020), 9.23 / 39.211 = 23.5% (2021). R&D 1,397 / 1,337 - 1 = 4.5%. Segment income / total assets 10,109 / 110,343 = 9.2%. ImmunoDiagnostics 912 - 802 = 110; clinical diagnostics 1,115 - 1,104 = 11. Restructuring 459 / 6,859 = 6.7% (2023). Microbiology 645 / 44,556 = 1.4%. Laboratory products 2,613 / 23,041 = 11.3% (2023), 2,407 / 23,984 = 10.0% (2025). Clario 0.45 x 371.5 = about 167, / 9,098 = 1.8%. LPBS capex / segment income 1,005 / 3,350 = 30%; Life Sciences Solutions 152 / 3,768 = 4.0%. Equity / assets 52,686 / 113,174 = 46.6%. Clinical research 7,915 / 44,556 = 17.8%. Eliminations Q2 565 / 501 - 1 = 12.8%. Instruments 7,301 / 6,292 - 1 = 16.0%. Revenue per employee 18,274 / 55,000 = about $332,000 (2016). Healthcare channel 1,788 / 44,556 = 4.0%. China 2,797 / 32,218 = 8.7% (2020). RPO 29.70 - 27.92 = 1.78 billion - segment margins, shares and growth. — 2015-2026 · publ. September 2026 · source ↗
    Method: Arithmetic on figures reported in Thermo Fisher's Forms 10-K and 10-Q, results releases, earnings calls, MarketsandMarkets and market data; operands shown in the source line.
Sources
Generated September 28, 2026